AREDS 2 Formula builds on the original, clinically proven AREDS Formula, with lutein and zeaxanthin replacing beta-carotene based on the AREDS 2 study.* This advanced AREDS 2 Formula contains the exact same levels of all six nutrients based on the latest clinical evidence from the AREDS 2 study. #1 doctor recommended brand.** 2 per day. Current/former smokers: This product is beta-carotene free. *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. **Data on file for #1 doctor recommended brand, Bausch + Lomb.